Smokerr - "I would hope you actually read the comments though it appears not. Read the post about the testing in Post 22. That is typical of someone who actually has done tests."
I went back and read it and part of it is an apples and oranges. Lubed bullet become necessary when you go over 1000 fps. Note all 22 bullets are not lubed, some like Rem have the gold coating (never looked up what it is)
I agree with Post 22. Chainfire is from the front. Now how to prevent it is subject to the gun you are shooting (actually the cylinder in the gun).
I also agree on what wads can do. I actually experimented with wads in front of a bullet (safety thing on .451 ball loads). I pulled the wad out from the end of the chamber I was firing but the rest had them in it. What I saw was a blast pattern on the very outer part of the wad and no penetration even to the middle.
In my former work world we called that a Flame Areastor. Batteries and fuel tanks. Open to air but a baffle system that does not allow a flame front to get through it.
That follows Post 22 test as well as others calling it a safety factor.
Where we differ is how well the lead seals. I have shot .451 sans wads and no chainfire. I think its iffy and don't do it usually without wads. Somewhere .451 and below you do get chain-fire if you are counting on a lead seal.
From his account it sounds like he had loose chambers, maybe oval. As that is not going to seal, then yes a Wad is an answer. Ergo the gun (or the cylinder).
Uberti and Pietta call for .454 and Ruger .457 balls.
My 76 x ASP has a tapered chamber, no lead ring cut but it seals solidly.
I look forward to the response. I would prefer some latitude to the affect, I am not sure you read post 22. Being a former tech and mechanic I lived in a world of shaded nuances. It could work fine, it could be broke and it could be in between.