I am no expert by any means, but I can tell you what my set up was.
*TC Renegade stock
*Green Mountain LRH barrel, stainless steel with a 1-28 twist
*Green Fiber optic front sight, .04''rod
*Lyman 57SML rear peep sight
*Bullshop 460 grain Nex bullets(made in Montana)
*Oversized wool wad between powder and bullet
*2F Swiss black powder, 85 grains weighed.
I practiced shooting up to 200 yards. I was able to consistently hit a target the size of a bread toast at that distance.
I ended up shooting my bull at 208 yds.