I'm using 60gr ffg in my .45, 80gr fffg in my .50, used 85gr fffg in my .54, and never more than 100gr fffg in my .58. I use 100 -120gr fffg in my .62, and have used ffg to similar results by bumping the charge another 20gr, all Goex.
The furthest I have shot and taken deer was 125yards+, but...