A big part of it all George is about the consistancy of the load.
Each shot deposits a given amount of powder fouling, and if that deposit isn't considered during a shooting session the bore conditions change.
Some guy's use a patch lube that's wet enough to push fouling down with the patched ball.
Others will swab the bore as an individual part of the process of loading.
Still others (where legal according to range rules) blow down the bore to soften fouling.
The ways are many, I don't want to promote one way or another as it always leads to great depate, but they all boil down to paying attention to the details.
Bore fouling can be different from day to day with weather conditions, cold, hot/dry, hot/humid as well as different with the various powders.
Seating pressure is another variable.
If you really want to wring the most out of your rifles this will be the best money you've ever spent.
http://www.blackpowderrifleaccuracy.com/
Kinda interesting, I just looked at the site, I was #284 when I bought the "System".