Can't help you with your CVA. I do use them for hog hunting in my 50 caliber T/C, factory original 1:48 barrel. My best groups come with 90 gn charges of Goex 3f BP. When working up a load for that rifle, I tried TC's Maxi ball, PA Hunter, Buffalo Bullet Co. 385's, TC Maxi-Hunter 275, TC Maxi-Hunter 350's. Nothing came close to the Hornady for groups at 50 yds. out of my rifle. The Great Plains has a hollow base, with a pretty thick skirt. IMHO, it takes a pretty stout load to fully expand that skirt and take full advantage of it.
90 gns. of 3f is a right stout load, and may be more than necessary but it gets me 1 hole groups from a rest @ 50 yds.
The last hog I shot with one was an approx. 140 lb. boar. 20-25 yd shot through the atlas joint (where the spine attaches to the skull). I was in a tree stand, he was "Snuffling" along a trail, head down. The Great Plains bullet penetrated the spine, dropping him on the spot...passed through the entire chest cavity diagonally, stopping in the brisket. Retained wt. of the recovered bullet is 350 gns. It expanded into a nearly perfect mushroom measuring .875 in.