my 45. is dead nuts at 50 yards and a tad low at 100. i use a 65 grain cgarge of fff goex and a .445 hornady rb. there is absolutly no doubt that i could have put a ball in that deers shoulder/ heart / lungs at 100 but there are just to may variables to consider. trust me i wanted and i had the sights tigt to his neck but that little voice just told me that is was not the right time! i have killed some big bucks and this one was BIG!!! at 60 yards he was dogging a doe through heavy brush but his heavy mass, bright white, high rack was clearly visable, was all of a 10 point if not more. i choose to hunt with my 45. and its limitations. i am not one bit sad that i didn't take the shot. maybe this buck will breed 10 does this month, maybe i'll put a ball in his neck this week, who knows. i do know that he is as we speak a truly huge, healty, unharmed, king of the woods Adirondack buck that will hopefully spread his genes on. oh yeah, next saterday i will be hunting with the same ole trusty .45, Miss Fish. maybe i'll get the 20 yard, broad side, slam dunk shot and then i'll know it was ment to be.