Seneca .45 :
I read the Thompson center (T/C) manual for the max load. I am not recoil sensitive but there is no need to beat up my shoulder and cheek or stress the rifle stock with heavy loads (80-90 grains FFG/FFFG). For fun, I started with 40 grains FFFG GOEX powder and roundball @50yrds. The result was great accuracy. I increased the load in 5 grain increments and continued to get great accuracy with slightly higher points of impact at 50 yards. As I arrived at 70 grains GOEX FFFG, the accuracy was still there so I extended the range to 100 yards. Still great accuracy but I needed 60-70 grains of FFFG to have vertical success on the bull's eye @100 yards. For 100 yards or less, I decided that 50 Grains GOEX FFFG was plenty.
Once happy with the roundball, I experimented with the T/C .45 maxiball. and the .45 LEE R.E.A.L. . I worked up an accurate load using the same procedure as above. Both performed great in my Seneca. For the two conicals mentioned, I settled on 60 grains GOEX FFFG for the happy medium of accuracy, hunting and recoil comfort.
These loads in the Seneca work great for targets, deer, and the occasional pig.
Imagine, I only use 70 grains GOEX FFG in my .62 smoothbore for shot and roundball. For my T/C .50 Hawken I use 80 grains GOEX FFG for Conicals and 70 Grains GOEX FFG for roundballs.
I have taken many deer and pigs with the .45, .50. and .62 roundballs and conicals with the above loads.
Please consider the game in your hunting area. Here, I do not have Elk, Moose or Grizzly. The black bear and puma are rare and protected in this state. Native Americans have not raided my relatives for almost 200 years. My choice of projectile and powder load reflect the conditions and legal game in my hunting area.
Dan
P.S.
@Firehole : In some of my guns, I feel that FFFG burns a little cleaner than FFG. One just needs to experiment.