While working up a turkey load for my 20 gauge smooth rifle several years ago I tried loads which were essentially that. I was working with 3F at that time, so I loaded 80 grains 3F, closely equivalent to 100 grains 2F, and a full 2 ounces of shot, #6 and #7 1/2. I got good patterns with both at 25 yards, even and dense, with about a dozen lethal hits on a full-size turkey head silhouette. Penetration was better with the #6 than the #7 1/2. I carried the gun loaded that way on a couple of hunts, never got a shot to test it for real. I continued working on the load, found patterns just about as good with 80 grains 3F and 1 1/2 ounce of shot, so switched to that because of the reduced recoil.
I've watched Mikes video, and am going to be increasing my small game loads for a while to see if his ideas work for me in the field. Loads similar to his, or even heavier, are described in the old literature as being routine for 'shooting flying'. Thomas Page, 1767, shot an equal-volume load of 123 grains powder and 2 ounces of shot.
Spence