I would try any of the flat-nosed bullets in that fast-twist .54 barrel. Years ago, I tried in vain to get someone to make me a .50 or larger, fast twist barrel for a slug gun. No one would then, but now they abound - and cheaply, too.
: The buffalo bullets from Hornady should be great killers of game and maintain the large calibre advantage.(in that fast twist)
: The maxiballs have a very poor shape and construction- having those great huge grooves and sloping nose. Combined they promote collapse of the bullet, rather than expansion. as Maxiball said, I mentioned their utter failure on moose when shot from the 48" twists. It is quite possible, a shorter bullet, like a 300gr. REAL might be OK in that twist, I don't know. The 370gr..50 Maxiball and 400gr.+ in the .54 cal were utter failures & wouldn't go in a straight line. They turned on bones without breakng them and skidded around and in the soft areas of the body, just as Forsyth said the understabilitzed slugs would. We want that bullet to smash the bones and go in a straight line across the moose's body, to smash the off shoulder, or exit the hide on the off side, not turn on a rib and go into the guts instead of penetrating the rib and holing both lungs. When we got the guys to switch to RB's, even though they weren't very accurate, a moose has a kill zone, almost 36" in dia. and the rifles had enough accuracy to hit those out from 50 to 100yds. or so. the guys started killing theri moose wiht 1 shot, instead of having to shoot them limb from limb.
: By all means, try several of the slugs. The best will allow shootng without having to clean between shots, at least 4 or 5 shots without having to swab the bore. Perhaps, swabing berween groups when testing would be what to try for. A poor shot, due to glancing on somnething unseen, or flinch or whatever, causing a fast second shot to need to be made, but not being able to make it due to fouled bore, is unaceptable. You've got to be able to shoot several shots without having to clean.
: The Hornady Buffalo bullets, solid base, shot well in my .50-70 with the addition of some comercial SPG lube. Those, in 54 would be a good place to start.