The first reference to the actual making of wine in what is now the United States is in the report of his voyage to Florida in 1565 by the rich and respectable pirate Captain John Hawkins, afterwards Sir John. In 1564 the French Protestant Admiral Gaspard de Coligny had sent out a colony of Huguenots to the mouth of the St. John's River in Florida, and there, at Fort Caroline, Hawkins found the wretched survivors a year later on the verge of starvation. Hawkins sold them a ship and left them food, noting with some disapproval that, though they had failed to grow food for themselves, yet "in the time that the Frenchmen were there, they made 20 hogsheads of wine."[20] It must, one supposes, have been made from rotundifolia grapes””that is, from the muscadine.
Recent inquiry into this story, which has long been received without question, shows strong reason to doubt it. The testimony of the French themselves is that they had no wine at all except for what they got from external sources.[21] After the French had been driven away from the Florida coast, the Spaniards made a settlement on nearby Santa Elena Island””now Parris Island, South Carolina””and a vineyard was reported as planted there by 1568. There is some evidence that the vines planted were vinifera, and, if so, the odds are overwhelming that no wine was produced from them.[22] But of course the Spanish colonists were surrounded by abundant wild grapes and so could easily have made the experiment of trying them for wine: in all probability they did. In any case, Parris Island may claim to be the place where the first attempt at winegrowing in America was made.