According to the Pedersoli catalogue, the Tryon Creedmoor, or S.229, has a 1:21 fast twist barrel, and uses .451 long (500 grain) bullet, mold 318-451.
The Match version which has the same barrel uses a .450 Minie (310 grains). (The Mortimer with the same fast twist barrel says both work).
Open sight versions in 45 caliber, the S.219 and S.224 with 1:48 twist use the .445 round ball and a 307-445 mold.
The difference between the 1:21 twist barrels and the 1:48 twist barrels is substantial. So I would recommend being absolutely sure what barrel you have before buying a mold.