For target work, I like to use a bore size or greater ball, I shoot a .405 out of mine. Now this isn't something that you would want to do while hunting because I have to use a hammer to tap the ball to get it started. For hunting I would use a .395 or .390. As far as powder is concerned, for targets I use 60 gr of 3F because I don't have to change my sights for 25 and 50 yards. To be honest with you, I couldn't tell the difference in my groups between 50 and 60 grains but I prefer 60. For hunting, just use the same charge as you do for target. The ball is going to pass threw whatever small game you shoot at so, I would just use what you're uses to.
Not with this said, take it with a grain of salt. Do your own testing and have a good time. By doing so you'll get to know your rifle.