Hmmmmmm :hmm: I don't have the answer for that one either. I know that there were a lot of barrels in the smaller calibers that had pretty slow twists. I have a .36 with a 1:66 twist that seems to shoot pretty well. But if I were to attempt a SWAG, I'd say that it was because the larger masses of the balls for the large bores take more time to overcome their inertia start rotating and would, therefore, require a slower twist while the smaller masses of the smaller caliber balls overcome their inertia more easily and will work with a faster rate of twist. You want as fast a rate of rotation as possible because the faster it rotates, the more stability it has in flight. This rotation is the whole purpose of rifling.
I'm going to take a look in my Ballistics book and see if it says anything about these rates of twist with respect to caliber for a round ball. I know it addresses rates of twist for conicals as a function of projectile aspect ratio and velocity but I don't know if it addresses twist rates for patched roundballs. :idunno:
It would seem that the 1:48 has proven to be a pretty good overall rate of twist in many, if not all, calibers. From what I have read, almost all Hawken rifles have the 1:48 rate of twist. It seems that most of them were made in the larger calibers (= or >.50). Again, I must say :idunno: