Yeah, I've shot them in a. 50 cal 1:48 twist Lyman GPR. They are pretty accurate, at least for me, but as mentioned before, not easy to load down a fouled barrel. I take a bore brush along when I'm target shooting them, and brush between shots. That helps alot, but takes much of the fun out of shooting them. I do like them for hunting deer though, they give me alot more knockdown power. A doe I shot with a Ball-et only made it 200 feet before dropping dead.