I tried it once and from that I would say no a friend had the same experience on the same day and we were using his pyro pistol powder, most use a bit of real BP then top of with the synthetic powders but nearly all reports show faster, more consistant ignition/accuracy with real BP in flinters, hopefully someone here will share a place close to you where BP is available, one can order it delivered most anywhere in the continental USA but the hazmat fee makes small lots pretty spendy, but it has nearly indefinite shelf life so it will keep. Good luck on your quest.My guess is that the do not mix powder warning is an attempt to prevent BP or the synthetics from being mixed with modern smokeless type powders? and a good general rule of thumb.