I always compress powder. BUT powder compression is not just leaning on the loading lever all you can.
For instance, when match shooting, after all these years, I can seat the ball slowly and then push with just a few pounds force and then fell the "crunch" of the powder being slightly compressed. Absent having a fancy spring loaded tension lever to make the compression uniform, it just takes practice. Kind of like when a first time learner gets behind the wheel of any vehicle and over steers and over compensates the other way to correct. It just takes a little practice. With my Ruger and Remmi repro I have been doing it so long, I can do it by feel. You just want to feel that "crunch" like gravel grinding together. It takes only a little force.
A friend built a cylinder loading stand that has a spring on the plunger so it does not put more than 12 pounds (IIRC) pressure on the plunger pushing the ball down. Compression helps to an extent, but uniformity from shot to shot is even more important. Compressing chambers to different amounts will adversely affect accuracy. And lastly, you have to be very accustomed to your gun and a pretty fair shot, to even know the difference between compression and not compressing.
to some folks compression means trying to press the powder into a pellet. To me, it means seating the ball against the powder with the same tight snugness every time.