I have done a number of these, I use the front leg bones, the ones under the knee.
If you are not in a hurry, just put them in your freezer for a year, then take them out, and with the aid of a pair of pliers, you can peal them like a banana. The bones will be nice and white, dry and ready to work.
If you are in a hurry, just skin them fresh. If you skin with the cut down the front of the leg you can tack out the skins with the dew claws attached and make cool stuff like shooting pouch flaps. Saw the bones in half at the length you want your handle. Boil them until you can get all the meat off.
When still warm, use sticks and wire to get as much remaining marrow out as possible.
I find the best way to bleach bone is with hydrogen peroxide, as it is easier on the bone and does not leave the bleach smell.
Now, make cutlers resin. 5 parts pine pitch, 1 part beeswax, 1 part dry moose skat or ash or powdered charcoal. Melt the resin and fill the bone when nice and dry with the resin. Heat the tang of the knife till bluish. A heat sink between blade and tang will preserve proper temper. I use vice grips with the teeth ground off. With the bone in a padded vice, slowly set the tang down into the bone. Between the fact that the resin was hot when you poured it in and is reheated by the hot tang, the resin fills all voids, drives out remaining fat through pores in the bone, re-enforces the knuckle attachment and gives you an egg shell fit. Before the resin is completely hard, use a dull knife and clean off the resin that overflowed.
For a redundantly secure job I usually drill a hole in the middle of the handle and peen in an iron rivet.
Hope this helps, good luck.