If this was a BP cartridge, it would be shot thorugh a rifled barrel. This question appears under the Smoothbore heading, so I suspect the man wants to use a foster style slug in his 20 gauge shotgun, fowler, or fusil. Being a smoothbore, rather than rifled, you have real problems with this slug expanding enough to seal the bore. Most 20 ga. guns are bored .615 to .620. Mine is larger. Even at .615, that is .010 larger than the diameter of the slug as it is listed. You can use .005 " patching with that kind of slug, but such thin material is not likely to survive the trip down the bore, even if it does seal. That leaves using a hard overpowder card wad, and then a lubed cushion wad under the slug to seal the gases, lube the barrel, and give support to the slug's rim. I also would use a over shot card to provide a smooth, hard, surface on top of the cushion wad to keep the cushion wad from trying to drive up into the hollow cavity. I think that will give the best accuracy combination.
If you don't mind shooting 5-8" groups at 50 yds, then go ahead and put that hollow based slug down on the powder without any wads, and hope it expands to seal the bore. If you will use a chronograph on these two different loads you will find major differences in velocity, and in shot to shot variations between the two loading systems. And, accuracy will be bushel basket size with the bare ball load. You could try paper wrapped slugs, but you would only be able to wrap once around the slug if you want to get it down the barrel of a smoothbore. Its a lot different than shooting a similar slug in a rifled musket.
I am shooting a .600 Round Ball, by contrast, in my .626" diameter fowler. That give me a lot more room to try different patch thicknesses, wads, etc.