I have used fillers (corn meal, grits) and not. I use a 22 grain charge and have not seen any change in accuracy between the two. But then again my accuracy with this revolver has been hit and miss shooting offhand. My observations on the fillers; put your powder in and fill the remaining volume of the cylinder with your filler, top with a ball and ram home. You do not need to measure the filler. The grits compact more than corn meal so it is possible to seat the ball below the face of the cylinder. The corn meal does not compress so much so you typically will get the ball closer to the face of the cylinder after ramming. Also, 35 grains fffg is the volume of the cylinder on my pietta. So you can fill it to the top, put on a ball and ram it home-get a big boom and cloud of smoke-feel like a real man!