Dale, when Pyrodex came out the main criticism was slower or
difficult ignition. Then Fadala and others addressed the issue.
Duplex loads were discussed. Caps back then were iffy. It is
important that the precharge be small. So 10grs of 4f with
50 grs Pyrodex in a Mountain Rifle is what is done. I use
5 grs on most subs. Lately I'm experimenting with Blackhorn.
The cons is it slows down loading. You do not mix the powders.
One is loaded before the other-not mixed.