Combustible cartridges don't load well for me in a '51 navy either, and I'm not inclined at this point to open out the loading port with a Dremel. They load better in my '61 navies, with the Uberti slightly better than the Pieta. I make my cartridges from 40 gram per square meter rag paper which is heavier than cigarette papers or curling papers and wipes out some of the advantage of using the Lee heeled .375 conical, but they still load easily enough to get them in straight. I have a '58 Uberti Remington on order, and am hoping that with a little work on the Lee .375 mold the gun will handle combustibles well.
In terms of charge, I'm a plinker and perfectly content with 15 grains in a navy, but that's not the maximum charge that can be loaded using a cartridge.
There's a bit of a learning curve to making cartridges, and making them for me is slower than loading loose, but they are quick to load in the gun, and extremely convenient in situations where the shooter isn't inclined to carry all the fixins or burn up range time loose loading.