I have a Deerhunter .50. Traditions makes these projectiles called Plinkers. The name implies they are for target shooting but I have taken several deer and hogs with the Plinker projectiles. My rifle like them best and with 100 grain Pyrodex P. BTW it has a 1:48 ROT. With a patched ball of .490 mine likes about the thickest, most moist patch you can get down the barrel without beating on it. There are some pre-cut oiled .020's from Track of the Wolf that work good with roundball in that rifle. I've shot the PA Concical with 80 grains of Pyrodex RS, or 80 grains of Goex FFFg. It will group 2 shots nicely and then starts opening the groups more and more unless you clean the barrel again. I've had some ignition problems with Triple 7 and with the factory nipple. With a Hot Shot and Pyrodex (or real black powder) no ignition problems, it is quite reliable.
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I have tried conicals made for 36 and 44 caliber revolvers and of course round balls. My experience and experimentation is limited because I instantly realized the conicals were harder to load, no more accurate and more expensive.