Well, all kidding aside, PBR, point blank range, (almost went off the tracks again) is one of my own favorite considerations when making shot decisions. I like to have the decisions made in advance.
Most ballistic calculators will calculate a PBR for any specific size group that you may be interested in. And, it's entertaining to play with the calculations as long as we don't take them too seriously.
For myself, my two favorite big game rifles, both 54s, are easily capable of putting 8 or 10 shots into one ragged hole benched at 25 yards. Very nice "internet groups". But by the time either of those guns are brought to bear at 50 yards, under typical field conditions they, and my eyes and shooting ability, are clearly at their limits at 50 in an offhand situation. That's with wind not being a major consideration. Wind is a gamechanger and increasingly so as wind velocity goes up.
Things improve with a field style rest when possible but not by much.
When looking at 100 yards it's hard to imagine a scenario where either of those rifles in my hands and with my eyes under field conditions could reliably make a well placed shot on a deer or elk.