At normal pistol ranges twist rate should not be a factor the average shooter considers. Most shooters agree that there is no advantage for a rifled bore over a smoothbore at 25 yards. If one can not tell the diference between rifled and unrifled why should 1/16, 1/48 or 1/66 matter unless it was making the gun shoot WORSE than a smoothbore?
I once owned a .38 pistol with a worn out bore. It keyholed every 158 grain bullet I shot from it but still managed to keep every slug in the kill zone at 12 yards and on the shilouette target at 25. It would have probably done much better with a round ball!
Single shot Pistols were always considered close range personal defense weapons and the vast majority of them were never rifled. Rifling is an attempt to turn them into the long range tools they never were.
If you are building a pistol for serious target work or long range shilouette shooting worrying about twist might be in order, but that is not "normal use or range" for a pistol.