I totally agree with Mike Roberts on this issue. Speed loading a muzzle loader is an invitation to several potential disasters. I was part of a cannon crew, and did the swabbing and loading of the barrel. The other men were afraid of the job. I wanted to do it, so it was done RIGHT! I knew how wet my swab was, and how dry I got the barrel before putting the next load down the barrel. We fire mainly blanks, but if that charge goes off under your rammer, what happened to Mike's friend can happen again to you.
Oh, when I am grabbing the rod, I tuck my thumb down next to my index finger, and simply grab the rod with my fingers, like a champanzese uses its hands. If you close the thumb around the rod, and powder sends it out the barrel, you natural reaction is to make a fist, and that will pop your thumb right off your hand. by using only your fingers to grab the rod for the hand-over-hand technique, if the rod is fired out fo the gun, the natural reaction will cause the fingers to open, saving you from all but a nasty skin burn. Don't believe it? Relax your hand so the fingers are curled down, and then get to near a candle flame. The natural reaction is to pull the hand back, and to straighten your fingers out! The opposite will be true when making a fist, requiring the thumb to close on the index finger or knuckles. You tend to tighten the grip, rather than open the hand. Make a fist around a steel rod and then put the end over an open flame to heat the rod. You will tighten and then release. That reaction is too slow to save your thumb from a driven ramrod with a jag on the end to catch the thumb as its shooting by.
The only time my hand is at the back of the handle on my range rod, or ramrod, is when I have run a damp patch down the barrel FIRST!, and I am now running a clean dry patch down to make sure the barrel is clean and dry before I load the next charge of powder. I can " Feel " the lands and grooves better when I hold the end of the ramrod doing this. However, the rest of the time, I run the ramrod down the barrel using the hand-over-hand method, never moving my hand more than 8 inches up the rod from the muzzzle. I have never even come close to breaking a ramrod, and don't intend to do so now.