I'm still trying to figure out how people actually get 40gr of powder into the chamber of a Remington Model 1858. A Walker, yes, easy, but a Remington? I can't get 40gr in a Ruger Old Army...
BTW, the usual load for a .44cal cap and ball revolver is around 25gr of 5Fg, but as the gentleman above notes, it's a good idea to start low and work up.