.50 cal is what I’ve hunted with. RBs and conicals. There was a time when I wasn’t that concerned on shot placement, that was many years ago. Now, the little that I hunt now, it has to be close to a perfect heart/lung shot. The quick death of the animal means a lot to me now. But even so, it depends on the individual deer. I’ve had them drop straight down and with the same shot placement had them run 100 yards. As to what is going on to cause that I don’t know.
Indeed, always going to be those strange cases that makes us scratch our heads. Still collecting data so thank you for your input.