For roundball, you measure out the powder (don't know what gun you have so I won't quote a load) and pour it down the barrel... (some people tap the side of their barrel with the palm of their hand to settle the powder in the breech area)
Next, take a lubed patch and center it over the muzzle, start a round ball with either a ball starter or your thumb...
Run the ball down on top of the powder in short, smooth strokes, don't grab the ramrod at the tip and expect to run the ball down in one stroke, if you have a wooden rod, this will break it and run it through your hand...
Once the ball in on top of the powder, tap it a few times with the rod to make sure it's seated firmly, (a good tip it to mark you ramrod at this level, that will let you know the ball is seated in the same place each time for this particular powder charge)
Here is the tricky part, many people forget: remove the ramrod and put it back where it goes... (yes, people do shoot their ramrods down range)
Now all that is left to do is to prime and shoot...