It might, T/C use to make shot shells for their Contender...
So, I know it could be done.
You would need a tall, thin wall shot cup/sabot to get the job done...
I would weigh out the shot and sabot to see if it is close to the bullet/ball weight normally used, if lighter, then powder would have to be adjusted for the weight of the shot charge...
If you do use this sabot with shot, you will also need a "overshot card", a round disc of light weight cardboard (like from a cerial box), shot cards can easly be made at home.
I would use the base of a .54 caliber sabot to get the size, just trace them and cut them out on the outside of the tracing line. You would want it a little snug...
This disc is used to keep the shot from draining out of the shot cup/sabot, just in case you don't keep the barrel pointing up all of the time. The loose shot would act as a barrel obstruction if it was allowed to float freely inside the barrel.