Guys I really do have to agree with Mike Roberts. 4Fg powder generates very high pressures very quickly. That is why it is not recommended by GOEX for use in anyyhing other than as priming powder. I would not worry so much about velocity, as pressure. Its the pressure that will wear out the metal( have you heard of metal fatique?) in a cylinder, and cause it to burst. I am less concerned about a barrel bursting these days, simply because the alloys used, but that vent liner may not stay in place, and I have seen nipples take an unexpected hike even with 3Fg powder!
Guys who use BP as a " booster " to ignite subs are using a trick that was used in cartridge guns when the primers were not all that good( mercury fulminate.) But a cartridge has its own tensile strength, to add to the chamber to protect the gun and shooter from excess pressures in the chamber, and of course, a brass casing is a " closed " system, where neither flintlocks, or really, percussion caps are.( You have only the weight of the mainspring holding the hammer on the nipple to keep the gases in the chamber from venting out the nipple. )
I cannot recommend to other shooters, and to new shooters that they ever use 4Fg powder in their barrels, even in percussion guns. That is like using large loads of Bullseye smokeless powder in a gun, mistaking it for Unique, or green dot, or 2400, or some of the other flake powders. I have seen modern magnum revolver cylinders burst using this propellant. I can assure you that the cylinders on BP replica revolvers are not heat treated, nor made from the same steels as are magnum revolvers.
Remember, in addition to the hole in the back of each cylinder for the individual nipple, there are cylinder bolt cuts in the walls of the cylinder at the side of each chamber, making a very thin spot in the wall where that cylinder bolt notch is cut. If the cylinder is going to burst, that is most likely where it begins. The next place will be at the rear, blowing out the nipple where the threads are either improperly cut, or worn down through corrosion.
The shooter is standing behind that nipple. His hand is underneath that cylinder bolt notch. On a Colt 1851 Navy revolver, only the face of the hammer is between the shooter's face and that nipple coming loose.