I agree with any wounding is terrible and unfortunately if you hunt, it will happen. But let's use the tree rat/deer differences. Sure you can injure either of these two animals the same way, but the margin of error is very different. If you are off 1 inch, to the front on the squirrel, it suffers. But the shot you probably took on that squirrel was probably inside of 30yds. and you were probably using a rest. On a deer, you maybe were shooting off hand, just because of the nature of the animal and probably shooting further. The nose is MUCH larger on a deer, there fore easier to hit...wrongly. I have lost wounded animals and if you are honest about it, you have too. But it is not something anyone tries to do, at least with the people I wish to associate with. I try to take the best shoots at the proper time and I feel that for my abilities, a head shot on a squirrel is my best shot. I have had gut shot squirrels make it to their dens also, because I had blown a boiler room shot. I hope all hunters consider their quarry and give all of their shots, their best shots.