paulvallandigham
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Considering how big Mule Deer can get compared to the whitetail deer more often hunted, only a neck or head shot should be expected to " Knock down " a mule deer, using a .40 cal. ball. Normally you would not expect a lung shot to have that kind of effect until you are shooting .58 and larger caliber round balls. Even a .54 is iffy on a larger animal like the mule deer. The .45, 50, and 54s will kill a mule deer very dead, but normally the deer will move off after being hit, without much reaction to the hit, when shot in the chest. Heart shot deer sometimes will react by rising up, before bounding off, and, of course, any deer shot through the spinal cord drops in its tracks. The spine is a lot smaller target than most people think, and hitting it is usually a miss of the heart/lung area shooting high.