It is a good example of the Law of Diminishing Returns.
Another interesting graph is shown below.
Although this graph is of a .50 caliber guns velocity, it also applies to any gun shooting a lead roundball.
What it is showing is the increase in velocity of a ball at 100 yards vs the muzzle velocity.
Basically, the faster the ball is traveling at the muzzle, the more velocity (and energy) it looses as it flys downrange.
While the ball with a 40 grain powder load lost about 430 fps at 100 yards, the ball that was shot with a 120 grain powder load lost about 840 fps.
The moral of the story is yes, increasing the powder load does increase the muzzle and downrange velocity but, the gains are not that great when one considers the amount of powder being burned.
Getting back to the original topic, the powder chamber in my Lyman looks like it is about 8mm (.315) in diameter X about 25mm (0.98") inch deep. (I don't have a way to actually check out the size with it way down in the bottom of the bore).
If these guesses are about right, that powder chamber would hold about 19 grains of powder.
If this is true, any powder load over 20 grains should compress when a patched ball is rammed down all the way.
Looking at the steepness of the first graph I posted, I'm guessing a powder charge of 30 grains would produce a muzzle velocity of around 750-850 fps.
When one figures the MV of a .45 ACP is in that ballpark, any small game animal within 60 yards would end up in the pot if the ball hit him.