Quoting from page 227 in Azel Ames book "THE MAY-FLOWER & HER LOG" Copyright 1901
Houghton, Mifflin and Company
The Riverside Pres
1907 (Second Edition)
"The arms and accoutrements (besides ordance) of the May-Flower Pilgrims, known on authority of Bradford and Winslow to have been brought by them, included muskets ("matchlocks"), "snaphances" (flintlocks), armor ("corslets," " curiasses," "helmets," "bandoliers," etc.), swords, "curtlaxes" (cutlasses), "daggers," powder, "mould-shot," "match" (slow-match for guns), "flints," belts, "knapsacks," "drum," "trumpet," "manacles," leg-irons," etc., etc. "Pistols" (brass) appear in early inventories, but their absence in the early hand-to-hand encounter at Wesagussett indicates that none were then available, or that they were not trusted..."
This was in 1620-1621 depending on the calender type you choose to use.
On page 228, a interesting list of things that a man named Josselyn gives in a booklet he wrote in 1629 for each average person wishing to make a similar voyage was:
""Armor compleat:--
One long piece (musket) five feet or five and a half long.
One Sword. One bandoleer. One belt. Twenty pounds of powder.
Sixty pounds of shot or lead, pistol and Goose-shot..."
The amount of powder and lead would indicate they were shooting a 3:1 ratio in their hand held guns.
In todays guns that would be a powder load of about
.45 caliber = 43 grains of powder
.50 caliber = 59 grains of powder
.54 caliber = 77 grains of powder
.62 caliber = 113 grains of powder
.69 caliber = 157 grains of powder
.75 caliber = 202 grains of powder
Of course all of these numbers are based on the weight of solid lead roundballs and the powder charges for the larger caliber guns shooting shot would be different.
For instance, a 12 bore shooting a 1 ounce load of shot (437 grains) would likely load about 194 grains of powder, or a 16 bore shooting shot would be about 145 grains if the ratio of 3:1 was held to.
I also have little doubt that the powder available in 1629 was not of as high of quality as the powder we now use.
Also, some of the powder per shot went for priming the pan.
The Pilgrims also had several cannon sized guns that they mounted by their town.