Long before I knew any better or had read any books about why I couldn't do what I was doing, I practiced at long ranges and hunted at slightly shorter ranges than I shot for practice. I won't post those distances here as a matter of ethics. However, the one young spike in the last legal light of the last day of the late muzzleloading season way back then that never took another step or even heard the shot that killed him was testimony that 90 gr of ffg behind a .490 pure lead patched round ball is lethal even when those charts say that said the ball shouldn't have had enough "killing power" to knock a feather off a titmouse's butt. All those summertime practice sessions told me that if the ball was sufficiently powerful to blow through the unrotted stump that I held my targets, they'd do the job on deer. Or bear. Or mutant walking killer stumps. Anyways, that buck fell where it stood.
Last year (actually '05 hunting season) opening day of the early muzzleloading season, I shot another at almost the same range, with identical results -- not another step, not even a jump, just slumped in place like a puppet on a string that's just been cut. My brother was a bit p-o'd that I took a shot at that distance, but changed his tune when he saw that the shot was a pass-thru dead-on in the vitals. And the deer here are big-bodied critters.
I am not advocating that you or anyone else do the same. I'm just saying that I knew my honest limits, kept my shots under those limits, and no chart or any other person can determine those limits. Just real life, real practice. The man with the experience is never at the mercy of the man with a theory.
By the way, it's a good thing that bumblebees don't know that science has proven that bumblebees can't fly. "Aerodynamically impossible." ...right...