Root: No, I would not use that screw hole. You don't use that screw for anything but to hold the bridle secure. It is there by itself for a reason & should be left there to do it's purpose..
I think you hve the sideplate too far back.
Take an exacto blade & scribe the edge of the ? "Ear" of the bridle & strip the lock as it should be to do this drilling & tapping & etc., kinda lay the sideplate over the inside of the lock, the holes should hit in the places the photo as you indicated, unless you are using a small siler or the wrong plate for a I.Haines. I guess it is a I.Haines is it not ? & large Siler lock ? that is what the sideplate indicates to me. And if so the front hole should hit just behind the frizzen spring & the rear one at the thick part of the pan side that I call the bolster.
Also as I mentioned in one of my above step to step posts, you will find that I stated that sometimes the bolts will not line up Exactly straight across, such as in 90 degrees. This is nice to have, but it just dosen't always turn out that way, depending on the Lock, Inlet, Lock size, Sideplate size/style, etc. Sometimes that bolt well have to be at a slight angle to hit the meat right to the rear of the pan, just like the dot you had in a previous post. Now if it is up Close to the shoulder of the bridle "Ear" I am going to call it (for lack of a better term) it is not a big deal but it should not pressure against it.
Most of the time I have my barrel back perhaps a lil further than you have & my rear bolt goes THRU the lug as you are calling it. If you are hitting the edge of it you will just have to notch it out there. However it is important that this lug doesn't put any stress on the rear lock bolt.
Also, if you have not done the front bolt yet or inlet the sideplate at all, you can move the sideplate forward slightly possibly & then you will drill Thru the Lug as you call it & hit the bolster where you need to.. It appears you have the sideplate just a little too far back, maybe 3/16" or so.
The next question that comes to my mind in this, is did you set the position of the vent/pan/front of the breechface & etc...... ? Is the vent in front of the breechface or into the side of the breechplug ?
Some guys put then right on the edge of the face of the breechplug, but I like my vents in front of it so the threads of the vent liner doesn't intersect with the breechplug threads & also I think you get less fouling of the vent with it in front of the breechplug face just a tad.
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This is a Large Siler lock on a I.Haines I recently built. If you look you can clearly see the position of the lock bolt holes both front & rear.
Also if you look, you will see the Front bolt hole is just a tad high, but still covered by the frizzen spring on the outside. This was purposely done to keep from hitting the RR hole as I just did have roome to get the bolt in thru without hitting the RR channel & the barrel.
NOTE: This is a LH lock but that has no bearing on the bolt positions.