IMO, yes, a sprue left on the ball can try to effect the flight of the roundball.
It will have some success if the roundball is fired out of a smoothbore but fired in a rifled barrel, its effect will be almost nothing.
Some of the effect is due to the added weight and some is due to the aerodynamic forces caused by of the shape.
Lets say the forces are trying to make the ball turn to the right.
If the ball is fired out of a smooth bore and it is not spinning, the ball will be deflected to the right.
Now, if the same ball is fired in a rifled bore, as soon as it leaves the muzzle the ball starts to turn right but immediately the ball has rotated and now it is trying to force the ball down and to the right. Then as it rotates further it is trying to force the ball straight down followed by a further rotation and a corosponding force down & left, left, up & left, up, up & right and so forth.
The final result of this is the rotation causes the force to rapidly be directed in all directions so the forces cancel themselves out and the ball flies, true to the target.