For the TC 36 Seneca at least, the manual loads are way heavy. Had little luck with mine until I tried going light. FWIW, 20 gr. Pyro P behind a .350 roundball with a .010 patch always worked wonderfully well in my 36 Seneca. 25 gr was good too, but the groups opened up at 30. Even 10 gr worked pretty good. I can't conceive of how bad loads heavier than 30 gr would shoot.
I know you're stuck with 2f Wano; but give light loads a try. Heavy loads may have already wrecked your nipple.
The 36 is a squirrel/small game/fun target gun, not a deerslayer. That's what the 50s are for.