Can't say about a Remington replica but I use it in my New Model Russian which has a VERY tight BC gap and it doesn't bind up the gun. Tried real BP, 777 and Pyrodex and couldn't get thru a full cylinder without binding. APP will get me thru a full day cowboy shoot and then some.
Most of my experience with APP has been with cartridge guns (44 Russian, 45LC, 38 Special). I've done a little bit with C&B. It does seem to like a lot of compression in a C&B or you get punky sounding loads, similiar to Pyrodex. When I load it in cartridges I give it a good 1/8" of compression.