I'm not so sure that it can't be done. According to a man's research into combustable cartridges has shown that the revolver powder used back during the CW era was more akin to 4F Swiss powder. Here's some quotes from his research that was given the OK to post:
Major Symington describes Colt's combustibles as, "The larger bullet was .456 in. diameter, and weighed 230 grains; the charge of powder weighed 20 grains. The small bullet was .383 in. diameter, and weighed 120 grains; the powder charge weighed 12 grains. The powder of both sizes of cartridges was of very fine grain called sporting powder, manufactured specially for these arms...."
After test firing Colt's combustibles, Major Symington reported, "The severity of shock [recoil] was due to the rapid combustion of such fine grained powder, particularly noted in Colt's cartridges, the powder of which is of special make.....'.
On page 552 of "THE GUN" (TG), the powder granulation illustration (Photo "D") shows "Revolver Powder" to be very fine grained exactly as Major Symington described the Hazard gunpowder used in Colt's combustible cartridges. The Hazard Powder described by Major Symington, and the "Revolver Powder" illustrated in THE GUN, is practically identical to FFFFg granulation today.
In the section on "Black Powder" in UNDERSTANDING FIREARMS BALLISTICS (UFB), author Robert A. Rinker's clear explanation of gunpowder characteristics, clarifies the Hazard Powder Company decision to provide FFFFg sporting-grade gunpowder for revolver use. "Experience and experimentation taught early gunners that particle size controlled the speed of combustion...............FFFFg was the smallest particle with the fastest burn rate and is used mainly in handguns." (UFB, page 23).
With a bit of thought, it becomes clear why the short chambers of a revolver's rotating breech would require a special powder capable of rapid combustion. Obviously, coarse-grained musket and rifle-grade gunpowders designed for use in barrel lengths of 30 inches and longer are not going to perform efficiently in a combustion chamber averaging a bit over an inch in length. With that bit of reasoning in mind, the Hazard Powder Company decision that very fine grain (FFFFg) gunpowder was best suited to the percussion revolver's combustion dynamics makes a lot of sense.
Hazard Powder Company's "Revolver Powder" was a fast-combusting FFFFg made from high performance Sporting-grade gunpowder, providing the most power possible from a given charge of gunpowder! This very potent Hazard "Number 1 Pistol Powder" is precisely the "First Quality Cartridge Powder" Hazard provided to Colt, D.C. Sage, H. W. Mason and other manufacturers of revolver combustible cartridges.
Now, before anyone runs out to buy a can of Swiss Blackpowder FFFFg to stuff in their favorite percussion "smoke wagon", be aware that FFFFg can be VERY DANGEROUS, ESPECIALLY in a revolver, unless you precisely understand the problems unique to FFFFg, that can arise from FFFFg use in a revolver.
Loaded properly with due caution, and with CORRECT charges, FFFFg is perfectly safe, and makes an excellent percussion revolver propellant. Near the end of this article I will detail the dangers that can arise from FFFFg use in a revolver. By understanding the possible dangers that can arise with improper use of FFFFg, the proper and safe use of this very fine grain powder in revolvers will be very clear.
As explained earlier, "Revolver Gunpowder" of the period from 1855 to 1875, was revealed to be sporting-grade gunpowder in FFFFg granulation. Combustible cartridges made by Colt's Cartridge Works used very fine grain sporting-grade gunpowder as documented by Major John Symington in June 1860. Major Symington of the Allegheny Arsenal near Pittsburgh, Pennsylvania, had dissected and test fired Colt's combustibles in .36 and .44 caliber, detailing their construction and performance in his June 1860 report to Chief of Ordnance Colonel Henry T. Craig.
Major Symington did not like Colt's combustible cartridges, because they recoiled sharply when fired, and because Colt's prices were too high. For test purposes, Major Symington constructed revolver combustibles at the Allegheny Arsenal, using tissue paper (similar to gift-wrapping tissue) envelopes and replacing the very fine grain sporting grade gunpowder with fine grain (FFFg) rifle grade powder. He thought the FFFg still generated too much recoil and recommended using musket-grade powder to keep recoil light! It appears that Major Symington was more interested in an easily controlled handgun rather than maximum power.