YOu have similar " problems" shooting out of tree stands. Actually, the difference in POI is not that great. The ball will strike a bit HIGHER than if the same round were fired over the same distance on flat ground. Remember that the range is NOT going to be very long with open sights,and shooting PRBs. In steep hill country, you find lots of trees and brush obstructing your view, and the flight path of the ball. Those are greater problems than the minor change in POI on the target.
The Ball shoots a bit higher, when Shooting UP a steep incline, too, because its shooting away from Gravity, and can more easily ride the air. Downhill, the gravity actually helps the ball accelerate, maintaining its trajectory over a longer distance( within reason). A Round Ball has a HORRIBLE Ballistics Coefficient, and sheds velocity quickly going through air, no matter whether its being shot flat, down, or up.
You can generally use your gun's caliber to tell you how much velocity will be retained at 100 yds. shooting a PRB out of it. A .45 will generally retain about 45% of its Muzzle Velocity out at 100 yds; A .62 caliber will retain about 60% of its MV out at 100 yds. Shooting any Round Ball above the Speed of Sound actually will cause the ball to lose more velocity faster, with NO NET gain out at 100 yds, the faster the MV used.
On a scouting trip to the area you intend to hunt, take a cardboard box with a target already stapled to it, and place it down hill, from some point, and climb the hill to shoot at it. Fire at least 2 shots, but 3 is better. Then put that box Up slope, and fire a couple of more shots.(Make sure there is a good tree, or rock behind the box to serve as a backstop for your ball.) That will give you some better idea of whatever change in POI you can expect from you gun, with your chosen load, at those ranges. That observed change in POI will help you learn how much to hold over or under a target at those distances, on those slopes. :thumbsup: