Welcome to the insanity, Chris !
Some things to think on/try:
* Shots 7" high @ 50 yards will be at least twice as high @ 100yds - so think about what the ranges may be where you're hunting.
* There are two ways to change the rifle sight's elevation of the point of impact (POI) - lowering the rear sight or raising the front sight.
Raising the front sight lowers the POI; lowering it raises the POI
Raising the rear sight raises the POI; lowering the rear sight lowers the POI
If you run out of adjustment, one sight or the other needs to be changed accordingly
* The heftier the powder charge, the faster the projectile will exit the barrel, lowering the POI somewhat.
* Using a .45 & a conical boolit, I wouldn't use less than a 60-70gr charge for deer.
* If you're shooting with the rifle resting on sandbags, the firmness of the front bag will throw shot higher than the POA (point of aim).
Keep messing with all those things - if nothing else, the practice will help you with getting a deer/etc.