Personal preference is to use stout powder charges for big game hunting and while 99% of my shots are 25-40yds, I very rarely get and inside stop and don’t want to...my .45cal deer load is 90grns Goex 3F.
This is a .440" I recovered from a 6 pointer at
60yds...broadside shot, ball broke a rib going in, plowed across the internals passing through the heart, and stopped bulging the hide on the far, inside his off leg...I suspect had the leg not been there against the hide, the ball would have completely passed through.
The ball did not flatten to a diameter hardly much larger than the .440 to begin with...just looks like a little 'igloo'...you can see the mark on the flat side made by the breaking rib. Didn't damage edible meat with good shot placement for a heart shot.