I would agree with everything said regarding your cleaning regimen and choice of propellant.
It may be worthwhile, though, just to rule everything out, to check your alignment.
If your cylinder is still loaded, carefully remove it from the revolver. Remove the caps from the nipples. Remove the nipples with a proper wrench, and dump out any residual powder through the nipple seat holes. Insert a wooden dowel or brass rod through each hole in turn, and use a wood, rawhide, or plastic mallet to drive out the stuck balls. Clean and lubricate your entire revolver, and reassemble it.
Next, find a straight hardwood dowel about a foot long. It should be a slip fit in the bore of your revolver, with minimal wiggle, so you may need to start with a 3/8" dowel and plane or sand it down so it will just slide in the bore.
Be certain that the firearm is unloaded. **** the revolver, and slide the dowel into the bore, all the way into the chamber of the cylinder until it contacts the base of the nipple inside the chamber. The rod should slide freely all the way in. If you feel it bump against the edge of the chamber mouth, that chamber may be out of alignment with the bore. If the rod won't go into the cylinder at all, you really have an alignment problem. Repeat for each chamber, and mark any that are out of alignment.
If any of them don't line up, you definitely need the services of a gunsmith who understands revolvers. Depending on how much you have invested in this firearm, if there is a serious alignment problem, you might just have a wall hanger.
A problem of that severity is unlikely. If it's that far out of alignment, there would probably also be a problem with the hammer impacting the nipple. The forcing cone may actually "forgive" a slight misalignment, and all of the fellows who responded previously gave excellent suggestions for troubleshooting. We are just covering all the bases here. However, if the balls are moving in the cylinder and still not exiting the chamber, it may be worth checking. Might be worth checking, anyhow, as proper alignment may help with accuracy once you get 'er shooting.
Notchy Bob