Herb said:"...The bull might be facing me, requiring a frontal shot through the shoulder bone.
Or facing away, with a shot through the paunch and liver and forward.
Or in brush.
Or caked with mud from his wallow..."
Or you're lined up for a perfect standing broadside shot to the heart and he starts to turn just as the sear breaks, now you've got a big shoulder in the way by the time the shot executes and ball gets there...nothing to do with ethics.
Milk toast plinking loads are for playing range games at 25 yards with charcoal briquettes, not for big game hunting. When I make the decision to go after a big game animal, to know I want to kill him quickly and humanely, I leave the squirrel loads and the squirrel guns at the house and go with Whompability...an example of ethics.